South Bend is a city in and the county seat of St. Joseph County, Indiana, United States, on the St. Joseph River near its southernmost bend, from which it derives its name. At the 2020 census, the city had a total of 103,453 residents and is the fourth-largest city in Indiana. Located just south of the border with Michigan, South Bend anchors the Michiana region and is 72 miles (116 km) east of downtown Chicago. The metropolitan area had a population of 324,501 in 2020, while its combined statistical area had 812,199. The area was settled in the early 19th century by fur traders and was established as a city in 1865. The St. Joseph River shaped South Bend's economy through the mid-20th century. River access assisted heavy industrial development such as that of the Studebaker Corporation, the Oliver Chilled Plow Company, and other large corporations. The population of South Bend declined after 1960, when it peaked at 132,445. This was chiefly due to migration to suburban areas as well as the demise of Studebaker and other heavy industry. Today, the largest industries in South Bend are health care, education, small business, and tourism. Remaining large corporations based in the area include Crowe, Honeywell, and AM General. The city's economy and culture are influenced by the nearby University of Notre Dame.